Microneedling with Advanced Serums

Why You'll Love It

  • Transforms overall skin quality — smoother texture, refined pores, brighter tone
  • Relatively painless — our device and technique make treatments highly tolerable
  • Tightens + firms — boosts collagen and elastin for a lifted, youthful look
  • Accelerates results — advanced serums supercharge repair and glow
  • Builds long‑term collagen — results continue improving for weeks

How The treatment Works

Microneedling with Advanced Serums is a fantastic treatment — it smooths texture, brightens the skin, and boosts collagen. But what truly sets our results apart is the quality of the serums we use.

Our serums are bespoke, best‑in‑class formulas designed to penetrate deeper during microneedling, giving you superior collagen stimulation and visibly better results than standard treatments.

And here’s what most new patients don’t realize: you’ll see dramatically better results when your skin foundation is strong first.

That’s why most patients begin with our Solutions by Age Foundation Plan. It rebuilds the deeper layers, strengthens your skin base, and gets your skin into “repair mode.” Once your foundation is rebuilt, our advanced serums work even harder for you — giving you smoother texture, tighter skin, and results that last significantly longer.

So yes — microneedling is great. But microneedling with our advanced serums after your skin is rebuilt…That’s where the real transformation happens.

Once your foundation is solid, Microneedling with Advanced Serums becomes a high‑impact upgrade for smoothing texture, shrinking pores, brightening dull skin, and boosting overall radiance. And if you want even more tightening and collagen rebuilding, pairing this with our RF Microneedling treatment delivers the strongest results.

Solutions by Age foundation levels:

  • 30s: early collagen support + prevention
  • 40s: deeper collagen rebuild + elasticity repair
  • 50+: lifting, firming, and strengthening the skin base

Whether you’re starting your skin journey or building on what you’ve already done, this treatment fits perfectly into your plan — and delivers the best results when your foundation is ready for it.

If you’re dealing with rough texture, enlarged pores, dullness, fine lines, or early signs of aging, microneedling with advanced serums is one of the fastest ways to rebuild smoother, brighter, firmer skin. This treatment doesn’t just create micro‑channels — it delivers regenerative serums deeper into the skin where collagen and elastin are made, giving you better results than standard microneedling alone.

Microneedling with Advanced Serums at Cosmetic Laser Solutions uses a precision stamping technique — not dragging — to protect the skin barrier, prevent micro‑tears, and deliver deeper, more even serum penetration.

This upgraded method produces a smoother texture, tighter skin, brighter tone, and faster collagen repair than standard microneedling.

Why our technique is different

  • Stamping, not dragging — prevents scratches, tearing, and inflammation
  • Even needle depth — consistent collagen stimulation across the entire area
  • Better serum delivery — micro‑channels stay open longer for deeper infusion
  • Less trauma — faster healing, less redness, better long‑term results

Why advanced serums matter

  • Exosomes rebuild cellular communication for faster regeneration
  • PN (PDRN) accelerates healing + strengthens the barrier
  • Bio‑revitalizers brighten, tighten, and improve elasticity
  • HA hydrates and plumps for an immediate glow

Standard microneedling only stimulates collagen. Microneedling with advanced serums corrects texture, tone, elasticity, and radiance at the same time.

What Patients Are Saying

“My skin has never looked smoother. The advanced serums made a huge difference — my pores look smaller, and my texture is so much better.”

— Verified Patient

“I loved that the microneedling didn’t drag on my skin. The treatment felt precise, and my fine lines softened within weeks.”

— Verified Patient

“This is the best my skin has looked in years. Brighter, tighter, and more even. I’m already booked for my next session.”

— Verified Patient

What is Microneedling with Advanced Serums

This treatment combines precision microneedling with targeted serums that penetrate deeper into the skin, accelerating collagen production and enhancing results far beyond standard microneedling.

The serums are selected based on your skin’s needs, allowing for faster texture refinement, improved radiance, and deeper rejuvenation.

Why You’ll Love Microneedling with Advanced Serums

This upgraded version of microneedling delivers faster, deeper rejuvenation by pairing collagen stimulation with high‑performance serums. You’ll see smoother texture, brighter tone, tighter skin, and a healthier glow — all with minimal downtime.

Before & After Results

Microneedling with Advanced Serums DermaBio
Microneedling with Advanced Serums DermaBio
Microneedling with Advanced Serums

Microneedling Serum Levels

Standard Level: Microneedling with Hyaluronic Acid

This level uses a pure hyaluronic acid glide to boost hydration, plump the skin, and improve overall radiance. It’s ideal for patients who want a gentle but effective collagen‑stimulating treatment with minimal downtime.

Advanced Level — Targeted Treatment Serums

This level uses advanced serums such as polynucleotides (PDRN), exosomes, or targeted bio‑revitalization blends to accelerate repair, brighten the skin, improve elasticity, and enhance collagen regeneration. These serums dramatically boost results beyond standard microneedling.

How Microneedling with Advanced Serums Works

Every microneedling series begins with 1–2 Exosome Microneedling treatments. Exosomes rebuild the cellular signaling pathways that control repair, allowing all post‑treatment procedures to achieve a higher level of rejuvenation.

Microneedling with exosomes penetrates deep into the skin to stimulate collagen and elastin synthesis, accelerate regeneration, and enhance the skin’s natural healing response.

After the exosome phase, we perform a series of 3 microneedling sessions using an advanced serum selected specifically for your skin’s needs. These serums target concerns at a cellular level — hydration, brightening, tightening, or texture repair — providing deeper correction than collagen stimulation alone.

Why we use Exosomes for Regeneration

We begin every microneedling series with exosomes because they repair the communication pathways between skin cells. When these signals are restored, the skin responds more efficiently to every treatment that follows. Exosomes accelerate collagen and elastin synthesis, reduce inflammation, and enhance cellular regeneration — creating a stronger foundation so the next microneedling sessions deliver deeper, faster, and more visible results.

PDRN Polynucleotides (Salmon DNA)

PDRN (polynucleotides) is used during the advanced‑serum phase when the skin needs deeper repair. Unlike exosomes, which rebuild cellular communication, PDRN focuses on healing — accelerating tissue regeneration, strengthening the skin barrier, reducing inflammation, and improving texture. It is ideal for acne scars, fragile or sensitive skin, and anyone who needs enhanced recovery and structural repair during their microneedling series.

Advanced Serum Options

After the exosome phase, your remaining microneedling sessions use one of our targeted advanced serums. Each serum is chosen based on your skin’s specific needs, making it easy to select the option that aligns with your goals:

  • Exosomes — Regeneration + cellular communication repair for faster, deeper rejuvenation
  • PDRN (Polynucleotides) — Healing, barrier repair, inflammation reduction, and texture improvement
  • Hyaluronic Acid — Deep hydration, plumping, and improved skin smoothness
  • 360 Bio‑Revitalization — Brightening, glow enhancement, and overall skin vitality
  • Firming Serum — Skin tightening, elasticity improvement, and lifting effect
  • Repair Serum — Post‑acne scars, texture irregularities, and structural repair
  • Whitening / Brightening Serum — Sun damage, pigmentation, and uneven tone correction

Benefits of Microneedling with Polynucleotide Serums:

Pairing microneedling with advanced serums dramatically enhances collagen production, speeds up healing, improves hydration, and delivers deeper, longer‑lasting rejuvenation compared to microneedling alone.

  • Smoother skin texture
  • Brighter, more even skin tone
  • Reduced fine lines and wrinkles
  • Improved elasticity and firmness
  • Faster recovery and reduced redness
  • Enhanced hydration and radiance
  • Better long‑term collagen remodeling

Benefits of Microneedling with Advanced Serums

By combining microneedling with targeted serums, this treatment accelerates collagen repair, enhances hydration, and improves overall skin clarity. The serums amplify the skin’s healing response, allowing for faster, more visible improvements in texture, tone, and radiance.

What to Expect During Your Treatment

Your treatment begins with a thorough cleansing and skin assessment. A topical numbing cream is applied for comfort. Once the skin is prepared, microneedling is performed while your selected serum is infused into the micro‑channels for deeper penetration and enhanced results.

  • Treatment time: 45–60 minutes
  • Comfort level: Minimal discomfort with numbing
  • Serum infusion: Customized based on your skin goals
  • Downtime: Mild redness for 24–48 hours
  • Results: Noticeable within days, continue improving for weeks

Treatment Plan & Recovery Timeline

Most patients begin to see improvement within days, with continued collagen remodeling over the next several weeks. For optimal results, a series of treatments is recommended, followed by periodic maintenance to keep the skin firm, bright, and hydrated.

  • Initial results: Visible within 3–7 days
  • Full results: Develop over 4–6 weeks
  • Recommended series: 3–4 treatments spaced 4 weeks apart
  • Maintenance: Every 3–4 months, depending on skin goals
  • Downtime: Mild redness for 24–48 hours

We recommend pairing your treatment with medical-grade skincare products such as:

Cost of Microneedling with Advanced Serums

Microneedling with Advanced Serums typically ranges from $450–$650 per session, depending on the serum used (PDRN, exosomes, or bio‑revitalization), treatment area, and the number of sessions recommended for your skin goals.

Who Should Avoid This Treatment

Microneedling with advanced serums is safe for most patients, but certain conditions may require postponing treatment or choosing an alternative option.

  • Active acne or infection in the treatment area
  • Open wounds or skin irritation
  • Recent sunburn
  • Pregnancy or breastfeeding (depending on serum type)
  • History of keloids or abnormal scarring
  • Recent use of Accutane or similar medications
  • Autoimmune disorders affecting healing

Microneedling with Advanced Serums is part of our collagen‑stimulation ecosystem, working alongside treatments like RF Microneedling, Skin Tightening, and Acne Scar Revision to rebuild texture, firmness, and overall skin quality. This treatment also integrates with our regenerative protocols, which support collagen renewal and enhance long‑term skin rejuvenation without relying on any single product line. For patients seeking a non‑laser option within our Skin Rejuvenation system, Microneedling with Advanced Serums provides a high‑performance pathway that fits seamlessly into our Solutions by Age approach for 30s, 40s, and 50+.

Frequently Asked Questions (FAQs)

Is microneedling with serums painful?

Most patients describe the treatment as very tolerable. A topical numbing cream is applied beforehand, which significantly reduces discomfort. You may feel light pressure or a mild scratching sensation.

How long does the treatment take?

Most appointments last 45–60 minutes, including numbing time, serum infusion, and post‑treatment care.

When will I see results?

You’ll notice early improvements within a few days, with full results developing over 4–6 weeks as collagen production increases.

How many sessions do I need?

A series of 3–4 treatments spaced four weeks apart is recommended for best results. Maintenance sessions every 3–4 months help keep the skin firm, bright, and hydrated.

Is there downtime?

Most patients experience mild redness for 24–48 hours. Makeup can typically be worn the next day, and normal activities can resume immediately.

If you’re exploring microneedling with advanced serums, you may also benefit from treatments that build collagen more deeply or target specific concerns. Many patients combine or progress to these options based on age, skin quality, and prior treatment history:

Special Offer — $99 Lift & Brighten Peel With Your Consultation

Kickstart your tightening and rejuvenation plan with a no‑downtime brightening peel for just $99 when performed during your in‑person consultation.

Book $99 Peel With Consult

Microneedling with an Advanced Serum to target specific concerns:

Microneedling with Advanced Serums DermaBio

Microneedling before and after photo

  • Collagen and Elastin stimulation
  • Smoother texture
  • Skin Tightening
  • Wrinkles
  • Sun damage
  • Scar Reduction
  • Enlarged Pores

Revitalize your skin with our cutting-edge Microneedling treatment enhanced with polynucleotide serums or exosomes.

Microneedling with Advanced Serums DermaBio

The Magic is in the

advanced serums

we’ve vetted.